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Before it's too late for your Child

July 2008
 

ABSTRACT: It is a confronting truth to realise that simply by having been brought into today’s modern world, your child may be at risk of developing a neurological defect. As a result of industrialisation, numerous harmful chemicals have been leaked into our environment, posing a major threat to people’s – especially children’s – health and development, and potentially giving rise to serious health conditions such as impaired learning ability, attention deficit hyperactivity disorder (ADHD), impaired neural development and even Autism and Asperger’s Syndrome. Some of these chemicals take hundreds, or even thousands of years to decompose. We cannot afford to wait patiently. The time has never been more urgent than the present to become proactive in minimising this significant threat to your children’s health.
 

KEYWORDS: ADHD, ADD, Autism, Asperger’s Syndrome, PCB, Kids Intelligent, development, childhood development, learning ability, neural development.
 

It is a confronting truth to realise that simply by having been brought into today’s modern world, your child may be at risk of developing a neurological defect. As a result of industrialisation, numerous harmful chemicals have been leaked into our environment, posing a major threat to people’s – especially children’s – health and development. Hazardous industrial chemicals have the ability to dramatically affect children’s quality of life, giving rise to serious health conditions such as impaired learning ability, attention deficit hyperactivity disorder (ADHD), impaired neural development and even Autism and Asperger’s Syndrome. While many harmful industrial chemicals have long since been banned from further use, a considerable amount of toxins remain present in our surroundings, in the food we eat, the water we drink and even within our own bodies. Some of these chemicals take hundreds, or even thousands of years to decompose. We cannot afford to wait patiently. The time has never been more urgent than the present to become proactive in minimising this significant threat to your children’s health.

Hazardous Chemical Compounds

Dioxins and Furans
Incinerators, coal and oil power stations, chemical and metal processing factories, open burning and accidental fires are all potential sources of highly toxic chemicals called dioxins and furans. Dioxins and furans are accidentally produced when other chlorinated compounds are incompletely burned. Due to their rife production, they have entered many world’s food and water sources, as well as infiltrating animal feeds and fertiliser, meaning humans often ingest considerable amounts of dioxins as a result of their meat and vegetable intake.

Polychlorinated Biphenyls (PCBs)
Until the 1970’s, the electricity and mining industries used large quantities of chemicals known as polychlorinated biphenyls (PCBs). The ability of PCBs to withstand incredible amounts of heat prompted their widespread use as heat transfer fluids in capacitators, transformers and electrical switching gear. They were also commonly used in everyday appliances such as refrigerators, as well as in paints and varnishes, lubricants, sealing materials, flame retardants and in strip lights and motorway lights. Although the active use of PCBs has been largely banned around the world, the presence of these chemicals in working machinery, and in our environment, is still of major concern. Indeed, high levels of PCBs have been found in Scottish salmon and fish farmed elsewhere, highlighting the importance of PCBs as a continuing contamination issue [1].

Brominated compounds
Televisions, computers, automotive machinery, furniture, videos and textiles all contain brominated flame retardant chemicals in order to prevent fires from starting or spreading rapidly. Many brominated compounds have properties similar to PCBs and dioxins, eliciting concern that these contaminants may act synergistically to mediate additive negative effects on people’s health and the environment.
 

Serious Impacts of Chemical Compounds

Currently, high levels of brominated compounds are known to exert neurotoxic effects on children in particular, significantly impeding learning behaviour and development [2, 3]. Further investigation has pointed toward negative effects on visual recognition in babies exposed to higher levels of PCBs in the womb [4], with later tests showing that at 4 years of age these children performed less well in short-term verbal memory tests predictive of learning ability [5]. Children of primary school age who have been exposed to PCBs throughout their childhood are also more prone to showing reduced cognitive development and delays in motor development [6].

Alarmingly, both PCBs and dioxins are known to have sex hormone-disrupting properties [7], which threaten to impair the ability of those exposed to PCBs in childhood to reproduce in later life. The fact that the impaired function of sex hormones caused by PCBs may cause “feminisation” among young male and female children is equally disturbing [7].

Further, studies [8] have shown a dose-dependent inverse association between PCB levels in children and the ability to prevent inappropriate behavioural responses – a common predictor for attention deficit hyperactivity disorder (ADHD). It has also been suggested that perinatal and childhood exposure to chemicals such as PCBs, dioxins and brominated compounds may be linked to the development of the brain conditions Autism and Asperger’s Syndrome [9-11].
 

What can you do???

The presence of hazardous chemicals in our environment is not a problem easily fixed. While many contaminants that were once commonly used such as DDT are now primarily obsolete, their presence continues to affect our health as they resist decomposition and are continually recycled through our water, waste, soil and food. Taking care when choosing the foods your family eats and the water they drink is essential. But when it comes to ensuring the proper brain, neural and learning development of your children, supplementation with the right ingredients to promote healthy growth and development is a must. There is an urgency when it comes to supporting your child’s development: the nutrition we receive during childhood has a significant influence on our health and development throughout life, meaning it has to be taken seriously from the outset.

 

PM Kids Intelligent Can Help

Acetyl L-carnitine
Kids Intelligent contains acetyl l-carnitine (ALC) for the development of the brain and nervous systems. In randomised, placebo controlled studies, ALC has been shown to enhance cerebral blood flow [12], as well as improve memory and response time [13], and cognitive performance [14-16].
 

Folic Acid
Kids Intelligent contains folic acid, also known as vitamin B9. Folic acid plays a key role in the production of myelin, which acts as an insulating sheath for neurons (nerve cells) and is essential for the transduction of messages throughout the nervous system and ongoing neural development. Deficient levels of folic acid have been linked with increased levels of the amino acid homocysteine and a decreased ability to produce methionine and tetrahydrofolate, both of which are essential for DNA synthesis and subsequent production of red blood cells (erythrocytes).

Bacopa monnieri
Bacopa monnieri is also included in Kids Intelligent to maximise cognitive and learning performance. Recent preliminary clinical research conducted in Australia [17, 18] has shown that bacopa significantly increases the retention of new information, improves higher order cognitive processes including learning ability, information processing and long term memory. Bacopa may also assist in reducing anxiety levels in patients with anxiety neurosis.

Omega-3 Fish Oils
Each cell contains a number of receptors, proteins, and enzymes within its membrane. Depending on the particular conditions of the moment, more fluid membranes readily remodel themselves in order to bind with different receptors and enzymes. This property is of particular importance in nerve cells, where the rapid reorganisation of cell membranes is paramount to optimising the signal transmission of the nervous system.

 

 

Figure 1. The Cell Membrane Phospholipid Bi-layer.
As can be seen, receptors, cholesterol, enzymes and other proteins are contained within a double layer of polarised phospholipids with hydrophilic heads and hydrophobic tails. The more polyunsaturated lipids contained within the membrane, the greater its fluidity, and the greater its ability to dynamically change its organisation to suit its environment and optimise cellular function.

 

PM Kids Intelligent contains omega-3 fish oils DHA and EPA that are stringently tested, and required to contain less than 0.1 PPM (parts per million) of PCBs and other heavy metal contaminants. Both DHA and EPA attach to larger phospholipid molecules in the membrane bilayer of nerve cells via chemical bonds. DHA (6 double bonds) and EPA (5 double bonds) are the most highly fluidising of all major membrane fatty acids, maximising the ability of nerve cells to remodel themselves and improve neurotransmission. Therefore, the greater the amount of polyunsaturated lipids such as DHA and EPA contained within a membrane, the greater its fluidity and dynamic properties [19].

The molecular benefits of fish oils explained above have been witnessed at a clinical level in numerous trials. The findings from one study revealed that 4 year-old children whose mothers had taken fish oil during pregnancy and lactation had better cognitive abilities [20]. Double-blind, randomised, placebo-controlled studies have further shown supplementation with DHA and EPA combinations shown to benefit attention deficit/hyperactivity disorder (AD/HD) [19], as well as mediating significant improvements in reading, spelling and behavior in children 5-12 years of age after 3 months of supplementation [21]. In light of this evidence, supplementation with fish oils may offer a safe and efficacious option for the prevention and minimisation of educational and behavioral problems among children.

Zinc
Kids Intelligent contains zinc for ongoing neural and cellular patency. Zinc deficiency is relatively common among individuals, with lower levels of zinc being linked with poorer cognitive performance. Low zinc levels are also evident in children with behavioural disorders, including those with symptoms associated with ADHD [22].

 

The nutrition we receive during childhood has a significant influence on our health and development throughout life. Eating a balanced diet is essential, but ensuring that children receive the necessary amounts of omega-3, acetyl l-carnitine, zinc and folic acid during the most crucial periods of their brain and neural development isn’t always easy. With all these ingredients, as well as bacopa monnieri to assist cognitive function and memory, PM Kids Intelligent is specially formulated to promote healthy development and wellbeing. For more information about Kids Intelligent, please click here.
 


 


 

 
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19. Kidd PM: Omega-3 DHA and EPA for cognition, behavior, and mood: clinical findings and structural-functional synergies with cell membrane phospholipids. Altern Med Rev 2007, 12(3):207-227.
20. Helland IB, Smith L, Saarem K, Saugstad OD, Drevon CA: Maternal supplementation with very-long-chain n-3 fatty acids during pregnancy and lactation augments children's IQ at 4 years of age. Pediatrics 2003, 111(1):e39-44.
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